Ongororo ichangobva kuitika yakaratidza kuti varume vanogamuchira majekiseni e testosterone undecanoate kwenguva refu vanowanzoomerera pakurapwa kwavo kana vachienzaniswa nevaya vanogamuchira majekiseni e testosterone propionate kwenguva pfupi.Zvakawanikwa zvinosimbisa kukosha kwemafomu ari nyore ekurapa kwe testosterone mukuvimbisa kuzvipira kwemurwere mukurapwa.
Chidzidzo ichi, icho chaisanganisira kuongororwa kwe data kubva kune varume vanopfuura 122,000 muUnited States, yakaenzanisa mazinga ekuomerera kwevarume vanobatwa ne testosterone undecanoate kune avo vanobatwa ne testosterone cypionate.Zvigumisiro zvakaratidza kuti mukati memwedzi mitanhatu yekutanga yekurapa, mapoka ose maviri aiva nemazinga akafanana ekuomerera.Zvisinei, sezvo nguva yekurapa yakawedzera kubva ku7 kusvika kumwedzi ye12, chete 8.2% yevarwere vanogamuchira testosterone cypionate vakaramba vachirapa, vachienzaniswa neakakosha 41.9% yevarwere vanowana testosterone undecanoate.
Dr. Abraham Morgenthaler, mubatsiri wepurofesa wekuvhiya padhipatimendi reurology yeBeth Israel Deaconess Medical Center paHarvard Medical School, akaratidza kukosha kwezviwanikwa izvi.Akataura, "Uchapupu hunoratidza kuti mamwe maitiro ari nyore ekurapa kwe testosterone, senge majekiseni akareba, akakosha pakuda kwevarume vane kushomeka kwe testosterone kuti varambe vachirapwa."Dr. Morgenthaler akasimbisa kukura kwekuzivikanwa kwekushayikwa kwe testosterone sehutano hunokosha hwehutano uye akasimbisa hutano huzhinji hunobatsira hunogona kupa testosterone therapy, kusanganisira kuvandudzwa kwehuga hweropa, kuderedza mafuta akawanda, kuwedzera musimba, kuvandudza mafungiro, kuwedzera kwepfupa, uye kunyange kuderedza. anemia.Nekudaro, kuziva mabhenefiti aya zvinoenderana nekuchengetedza kutevedza kurapwa.
Chidzidzo ichi, chakaitwa naDr. Morgenthaler nevamwe vake, vakashandisa data kubva kuVerdigm database, iyo inounganidza data rekodhi rekodhi rekodhi kubva kune zvipatara kunze kweUnited States.Vatsvakurudzi vakatarisa kune varume vane makore 18 uye pamusoro avo vakanga vatanga injectable testosterone undecanoate kana testosterone cypionate kurapwa pakati pe 2014 ne 2018. Iyo data, yakaunganidzwa mumwedzi ye6-mwedzi kusvika muna July 2019, yakabvumira vatsvakurudzi kuti vaongorore kutevedza kurapwa zvichienderana nenguva. kugadzwa uye chero kuregedzwa, kuchinjwa kwemishonga, kana kupedzwa kwepakutanga kunyorerwa testosterone therapy.
Kunyanya, kuomerera kwekurapa kweboka re testosterone undecanoate kwakatsanangurwa semukana wemazuva anopfuura 42 pakati pekupedzisira zuva rekugadzwa kwekutanga uye zuva rekutanga rekugadzwa kwechipiri, kana kupera kwemazuva anopfuura 105 pakati pekugadzwa kunotevera.Muboka re testosterone cypionate, kusatevedzera kwakatsanangurwa senguva yemazuva anopfuura 21 pakati pekugadzwa.Mukuwedzera kune kuomerera kwemazinga, vatsvakurudzi vakaongorora zvinhu zvakasiyana-siyana zvakadai sekuchinja kwehuremu hwemuviri, BMI, BP, testosterone mazinga, mazinga ezviitiko zvitsva zvemwoyo, uye zvakakosha zvinokonzerwa nenjodzi kubva kumwedzi ye3 isati yatanga jekiseni kusvika kumwedzi ye12 mushure mekutanga. kurapwa.
Izvi zvakawanikwa zvinojekesa kukosha kwekuita kwenguva refu majekiseni e testosterone mukusimudzira kuomerera pakurapa uye nekuwedzera mabhenefiti ekurapa kwe testosterone.Varume vane kushomeka kwe testosterone vanogona kubatsirwa zvakanyanya nemaitiro ari nyore ekurapa, kuve nechokwadi chekuenderera uye nekukurudzira kuzvipira kwenguva refu mukuvandudza hutano hwavo uye hutano hwakakwana.
Nguva yekutumira: Jul-07-2023